Stability of 1-Substituted Adenines

Author

Walter Frederick Floser, Union College - Schenectady, NY

Date of Award

6-1970

Document Type

Open Access

Degree Name

Masters of Science

Department

Chemistry

First Advisor

John Sowa

Language

English

Abstract

1-β-Hydroxyethyladenine was prepared by the reaction of ethylene chlorohydrin with adenine at 76° C. It was separated from the reaction mixture by use of a Dowex 50W-X8 cation exchange chromatography column and a linear gradient elution system. I was placed in aqueous alkaline solution for two weeks and checked at different intervals to determine its stability. I was also refluxed in an aqueous alkaline solution for 70 min. and its stability was checked. I proved to be stable under all conditions.

Recommended Citation

Floser, Walter Frederick, "Stability of 1-Substituted Adenines" (1970). Honors Theses. 2214.
https://digitalworks.union.edu/theses/2214