Synthesis of 2-(2,5-Dichloro-Phenyl) Tetrahydro-3 Methyl 1-4-H-1, 3 Thiozone-4-One 1,1-Dioxide and Study of the Sommelet Reaction Mechanism

Author

Alexander James Wall III, Union College - Schenectady, NY

Date of Award

6-1967

Document Type

Open Access

Degree Name

Bachelor of Science

Department

Chemistry

Language

English

Abstract

The text of this thesis deals with two separate, but inter-related prob- lems. The first is the synthesis of 2-(2, 5-Dichloro-phenyl) Tetrahydro-3 methyl 1-4-H-l, 3 Thiozone-4-one 1, 1-Dioxide. The second is a study of the Sommelet reaction which was employed in the syn­thesis of the above compound. This project was undertaken to complete the syn­thesis of a group of analogous compounds which have been synthesized by Wilson and Downer for the Sterling Winthrop Drug Company. The compounds illustrated below have been tested and found to have varying potential as central nervous system depressants.

Recommended Citation

Wall, Alexander James III, "Synthesis of 2-(2,5-Dichloro-Phenyl) Tetrahydro-3 Methyl 1-4-H-1, 3 Thiozone-4-One 1,1-Dioxide and Study of the Sommelet Reaction Mechanism" (1967). Honors Theses. 2138.
https://digitalworks.union.edu/theses/2138