Date of Award
6-2002
Document Type
Open Access
Degree Name
Bachelor of Science
Department
Chemistry
Language
English
Abstract
The amides of N-methoxy-N-methylamine or "Weinreb amide" have earned an important role in synthetic chemistry as both a protective group and as synthetic intermediates. We have discovered that the Weinreb amide of acetic acid, N-methoxy-N-methylacetamide adds to aldehydes to afford classic aldol products in good to excellent yields. The scope of this novel aldol reaction will be discussed.
Recommended Citation
Leyhane, Andrew J., "Weinreb amides : novel titanium enolate reagents" (2002). Honors Theses. 2083.
https://digitalworks.union.edu/theses/2083
Rights Statement
