Date of Award
Bachelor of Science
aging, cognition, function, healthy, aging, biomarkers
The current pilot study of the interactive Physical and Cognitive Exercise System (iPACES™) examined the relationship between biomarkers and cognitive change over three months of neuroexergaming, wherein older adults pedaled and steered along a virtual bike path to complete a list of errands (Memory Lane™). Executive function and saliva were measured at baseline, mid (6-week), and three months. Results revealed moderate to large correlations between executive function and salivary biomarkers cortisol, BDNF, and IGF1. These findings suggest that neuroexergaming interventions such as iPACES™ may impact both cognitive and neurobiological pathways and perhaps could be an effective way to promote healthy aging in the increasing older adult population.
Stark, Jessica, "Biomarkers and Neuropsychological Change: A Pilot Study of Three Months of the interactive Physical and Cognitive Exercise System (iPACES™) for Older Adults" (2017). Honors Theses. 262.