Date of Award

6-2017

Document Type

Open Access

Degree Name

Bachelor of Science

Department

Neuroscience

First Advisor

John Garver

Language

English

Keywords

aging, cognition, function, healthy, aging, biomarkers

Abstract

The current pilot study of the interactive Physical and Cognitive Exercise System (iPACES™) examined the relationship between biomarkers and cognitive change over three months of neuroexergaming, wherein older adults pedaled and steered along a virtual bike path to complete a list of errands (Memory Lane™). Executive function and saliva were measured at baseline, mid (6-week), and three months. Results revealed moderate to large correlations between executive function and salivary biomarkers cortisol, BDNF, and IGF1. These findings suggest that neuroexergaming interventions such as iPACES™ may impact both cognitive and neurobiological pathways and perhaps could be an effective way to promote healthy aging in the increasing older adult population.

Available for download on Friday, June 15, 2018

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