Date of Award
Masters of Science
1-β-Hydroxyethyladenine was prepared by the reaction of ethylene chlorohydrin with adenine at 76° C. It was separated from the reaction mixture by use of a Dowex 50W-X8 cation exchange chromatography column and a linear gradient elution system. I was placed in aqueous alkaline solution for two weeks and checked at different intervals to determine its stability. I was also refluxed in an aqueous alkaline solution for 70 min. and its stability was checked. I proved to be stable under all conditions.
Floser, Walter Frederick, "Stability of 1-Substituted Adenines" (1970). Honors Theses. 2214.