Date of Award
Union College Only
Bachelor of Science
The text of this thesis deals with two separate, but inter-related prob- lems. The first is the synthesis of 2-(2, 5-Dichloro-phenyl) Tetrahydro-3 methyl 1-4-H-l, 3 Thiozone-4-one 1, 1-Dioxide. The second is a study of the Sommelet reaction which was employed in the synthesis of the above compound. This project was undertaken to complete the synthesis of a group of analogous compounds which have been synthesized by Wilson and Downer for the Sterling Winthrop Drug Company. The compounds illustrated below have been tested and found to have varying potential as central nervous system depressants.
Wall, Alexander James III, "Synthesis of 2-(2,5-Dichloro-Phenyl) Tetrahydro-3 Methyl 1-4-H-1, 3 Thiozone-4-One 1,1-Dioxide and Study of the Sommelet Reaction Mechanism" (1967). Honors Theses. 2138.