Date of Award

6-2002

Document Type

Union College Only

Degree Name

Bachelor of Science

Department

Chemistry

Language

English

Abstract

Previous work has shown that chlorotitanium enolates of methylmethoxy acetate add to aryl aldimines in a stereoselective fashion. Aryl aldimines are non-enolizable, which contributes to their ability to add to the enolates. Previous attempts to add the enolates to enolizable alkyl aldimines were unsuccessful. By using a multi-component process in which the aldimine is synthesized in-situ, we have expanded the scope of this chemistry to the enolizable alkyl aldimines. Furthermore, the multi-component process has proven to be stereoselective for the anti-adduct.

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