Date of Award
Union College Only
Bachelor of Science
Cyclodextrin (CD) molecules can form inclusion complexes with many different types of organics due to the hydrophobic environment of the CD internal cavity. The flurophore-2-acetylnapthalene (2-AN) has a high flourescence intensity in polar solvents such as water. Therefore, its fluorescence is quenched when it forms a complex with a CD molecule and is contained in the non-polar cavity. By measuring the change in flourescence intensity in the presence of CD, we can calculate the binding constant for CD:2-AN complex formation.
Graves, Jason T., "The Binding of 2-Acetylnaphthalene to Beta-Cyclodextrin Polymers Studied by Flourescence Quenching" (1994). Honors Theses. 2044.