Date of Award
Bachelor of Science
In this study, a hybrid i+4/i+3 peptide will be synthesized. It is assumed that this configuration will enhance the formation of the alphahelix. Previous research has determined that a complete helical tum requires 3.6 amino acid residues. The hybrid peptide will include four residues followed by a second helical tum which will only encompass three residues. It is hoped that by slightly over turning and then under turning the helix, the stability of the overall helix formation will be enhanced.
Berger, Jay Steven, "Synthesis of a Hybrid Baldwin Peptide: A Study in the Factors That Influence Helix Formation" (1994). Honors Theses. 2041.