Date of Award
Bachelor of Science
Classes of compounds often have similar characteristics and activities. However, it has been showin in pharmacological studies that a small change in a structure produced by a substitution of an atom or a group of atoms on the original compound may cause a marked change in biological activity. When a certain compound shows usefulness as a drug, many variations of this compound are studied to see if a more useful form can be made. Two characteristics looked for are (1) effectiveness, which includes the onset or how long before the drug takes effect, and the duration or how long the effect lasts, and (2) lack of toxicity.
Hubbard, Van Saxton, "Synthesis of N-Benzyl-N-Methyl-β-Chloro-β(p-Chlorophenyl)-Ethylamine-Hydrochloride" (1967). Honors Theses. 1942.