Date of Award
6-1965
Document Type
Open Access
Degree Name
Bachelor of Science
Department
Chemistry
Language
English
Abstract
Normally, a diazoketone reacts with an acid to form a substituted methyl ketone. When a nucleophilic center is present at an α or β position of R, this reaction may lead to the formation of a cyclic ketone (11). It was the purpose of this research to investigate the cyclization of the aliphatic methoxydiazoketone, 1-diazo-4-methoxy-4-phenyl-2-butanone (I), when treated with BF3 in ether, to give the five-membered ring 5-phenyltetrahydrofuranone-3 (II).
Recommended Citation
Isser, Stephen Joseph, "The cyclization of a diazoketone with boron trifluoride etherate" (1965). Honors Theses. 1936.
https://digitalworks.union.edu/theses/1936
Rights Statement
