Date of Award

6-1965

Document Type

Union College Only

Degree Name

Bachelor of Science

Department

Chemistry

Language

English

Abstract

Normally, a diazoketone reacts with an acid to form a substituted methyl ketone. When a nucleophilic center is present at an α or β position of R, this reaction may lead to the formation of a cyclic ketone (11). It was the purpose of this research to investigate the cyclization of the aliphatic methoxydiazoketone, 1-diazo-4-methoxy-4-phenyl-2-butanone (I), when treated with BF3 in ether, to give the five-membered ring 5-phenyltetrahydrofuranone-3 (II).

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