Date of Award

6-2008

Document Type

Union College Only

Degree Name

Bachelor of Science

Department

Neuroscience

Language

English

Keywords

changes, alzheimer’s, analysis, disease, neuropsychological

Abstract

Research has demonstrated that exercise has a positive impact on neuropsychological performance in older adults (Colcombe, 2004). This prospective study investigates the neurocognitive, volumetric and electrical brain changes associated with strength training in patients with Alzheimer’s disease. Ten patients of the Stratton Veterans Affairs Medical Center who meet criteria for early Alzheimer’s Disease will be given a neuropsychological evaluation, a structural magnetic resonance imaging scan (MRI) and an electroencephleography (EEG) before and after a four-week long strengthening exercise program. Cognitive changes will be assessed through the analysis of the neuropsychological data, analysis for volumetric changes will be done on the MRI scans using voxel-based morphometry and analysis of the EEG will be done to assess electrical changes. Results may aid development of future treatments for Alzheimer’s Disease and other forms of dementia.

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